PIs conducting their own Investigator-initiated trials often lack the support and resources available in Industry-initiated trials. Thus, it is particularly important that PIs obtain maximum value from the limited resources available. As a company consisting largely of PIs, Refuah Solutions is very aware of this challenge. Thus, the decision was made at the outset to provide PI-Enroll to Investigators conducting their own Investigator-initiated studies at no cost. However, if the study is supported by Industry or multi-centered, a nominal subscription fee is applied.